Decreased responsiveness to ionomycin of isolated femoral arteries fromontancously hypertensive rats (SHR).
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چکیده
منابع مشابه
Spatial Memory in Spontaneously Hypertensive Rats (SHR)
The spontaneously hypertensive rat (SHR) is an established animal model of ADHD. It has been suggested that ADHD symptoms arise from deficits in executive functions such as working memory, attentional control and decision making. Both ADHD patients and SHRs show deficits in spatial working memory. However, the data on spatial working memory deficits in SHRs are not consistent. It has been sugge...
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Recent evidence suggests that angiotensin II (Ang II) upregulates phosphodiesterase (PDE) 1A expression. We hypothesized that Ang II augmented PDE1 activation, decreasing the bioavailability of cyclic guanosine 3' 5'-monophosphate (cGMP), and contributing to increased vascular contractility. Male Sprague-Dawley rats received mini-osmotic pumps with Ang II (60 ng·min(-1)) or saline for 14 days. ...
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Recent evidence suggests that angiotensin II (Ang II) upregulates phosphodiesterase (PDE) 1A expression. We hypothesized that Ang II augmented PDE1 activation, decreasing the bioavailability of cyclic guanosine 3 5 -monophosphate (cGMP), and contributing to increased vascular contractility. Male Sprague-Dawley rats received mini-osmotic pumps with Ang II (60 ng min ) or saline for 14 days. Phen...
متن کاملResponsiveness to potassium and calcium ions of isolated cerebral arteries.
TODA, NOBORU. Responsiueness to potassium and cakium ions of isolated cerebral arteries. Am. J. Physiol. 227(5) : 1206-12 11. 1974.Dog cerebral arteries (basilar, posterior cerebral, and middle cerebral arteries) with an outside diameter of 0.3-0.5 mm were helically cut into strips so that responses to IS+ and Ca++ could be investigated. The addition of 5 mM K+ produced a transient relaxation, ...
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We recently demonstrated that the interlobular artery (ILA) constricts in response to elevating renal arterial pressure (RAP), suggesting that the ILA contributes to renal autoregulation. In the present study, we examined the segmental myogenic responsiveness of the ILA in kidneys from Wistar-Kyoto (WKY) rats and spontaneously hypertensive rats (SHR). The tapered nature of the ILA allowed us to...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1989
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)56152-2